Robb Wolf – Mast Cell Activation Syndrome, Dry Fasting

Robb Wolf - Hernia Repair, Optimal Dietary Patterns for Healthy Aging Robb Wolf - Hernia Repair, Optimal Dietary Patterns for Healthy Aging


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News Topic:

Ruminating on soil carbon: Applying current understanding to inform grazing management

Show Notes:

Think Fast: The 252nd Evolutionary Lens with Bret Weinstein and Heather Heying

Dry Fasting Club Podcast

Dr. Ruscio MCAS Diet


Questions:

Mast Cell Activation Syndrome

Angie writes:

Hello Robb and Nicki –

I’ve been listening on and off for a few years, and I respect your perspective and the way rational and honest you might be in your strategy.

Some background, three and a half years in the past I received pregnant and early within the being pregnant I recognized that I wanted to handle my blood sugar with weight loss plan, which I efficiently was capable of do. About a yr after having the newborn I used to be recognized with methane SIBO, and went via a protracted therapy, which was profitable and improved my intestine signs drastically. After this, my levels of cholesterol and insulin resistance rating improved fairly a bit. The previous yr and a half , I’ve been carrying a steady glucose monitor, figuring out that I’m weak to kind II diabetes, and in hopes that I will enhance my blood sugar and regulate my menstrual cycle. I feel additionally it is be essential to say that I’ve had poor intestine well being since I used to be a baby, I believe I’m on the spectrum of PCOS – as I’ve an irregular cycle which is per these patterns, and I’ve excessive ldl cholesterol and have since I used to be 18 years previous, I have a tendency in the direction of irritation, and I’d say I’ve about 15# to lose. Despite all my efforts by making certain high quality sleep, consuming low carb – unprocessed and top quality meals, weight coaching 3x per week, managing my stress with meditation, and strolling 5-7000 steps per day, issues will not be enhancing. I’ve additionally tried berberine and numerous different really useful dietary supplements and there may be ZERO enchancment. My A1C three years in the past was 5.3 and most lately it’s 5.7.

The week earlier than Christmas I had the flu, 104*F fever for 4 days, congestion and a cough. Every week after having the flu, I seen that my head, shoulders, chest and different elements of my physique appeared to be getting sizzling and itchy like hives, plus I used to be having bloating and constipation/diarrhea, and bodily anxiousness (like tight chest, pulse within the 90s). Plus, my blood sugar was spiking after consuming a low carb meals and in different conditions that didn’t make sense. At a sure level I attempted to assist myself by taking electrolytes and further entire meals vit C. and issues continued to worsen. A pair weeks in the past my blood sugar was going as much as 125-130 and sitting there all day, even when I walked or exercised, after which it could go all the way down to 90-100 after I went to mattress. This has occurred a pair different occasions earlier than, and I couldn’t establish why this was the case. All this time I used to be consuming beneath 40g or much less carbs, round 140g protein, and 100g+ fats. As my signs received worse, I used to be led down the podcast rabbit gap of Mast Cell Activation Syndrome, and histamine intolerance, which I had realized about years in the past however didn’t essentially assume I match into this class.

In hindsight, I’m realizing that Mast Cell Activation Syndrome and or having excessive histamine hundreds within the physique, could clarify a few of the very unexplained and inconsistent patterns I’ve noticed whereas utilizing the CGM over the previous yr and a half. Some examples are, blood sugar spikes as much as 130 after taking dietary supplements (!), blood sugar spikes as much as 160 after consuming low carb soup with bone broth and greens, spikes after low carb meals that I would come with ferments or consuming sizzling chocolate (made with collagen, coconut milk, salt, cacao and stevia). And possibly, it explains why my blood sugar will go as much as 170-200 with any intense train, and my irritation takes days to recuperate from. And I’m questioning now, whether it is why I’m seeing no enchancment with my insulin resistance, even after constantly (not completely) doing all of the issues which are supposed to assist with insulin resistance.

Have you explored the connection between insulin resistance/kind II diabetes and Mast Cell Activation Syndrome? As I look again at my well being journey that is beginning to look very attainable to me, however I’m not a scientist or medical skilled, and know that there’s a lot I don’t perceive . And, I’m questioning in case you have explored this for your self in any respect?

But then nonetheless my query is! What is to be finished? Lymbic system retraining? Somatic experiencing? Making certain the physique has balanced and ample minerals? Low Dose Naltrexone? At this level I’ve tried many alternative issues, and man, if I knew what to do I’d do it.

I’m so curious what you guys assume, and could be so grateful to listen to from you.

Angie

MCAS and histamine after publicity

Jacob writes:

Hi Robb and Nicky,

First thanks very a lot for the podcast. It’s actually useful to listen to all of the totally different approaches to the well being questions individuals increase. On final episode you talked about you would possibly do the following episode on MCAS.

Personally I’ve put up viral POTS and a few kind of MCAS after my 2020 COVID an infection. LMNT helps me keep away from POTS signs and if I fully keep away from histamine from meals I do nice, with principally zero points. I discovered that I may even take grass fed beef liver drugs earlier than I’ve a meal with histamine and it appears to assist me keep away from the problems.

I’ve two questions. First, do you could have any expertise on how the liver drugs assist me to not get beat up after I take them prior? It appears to have one thing with pure DAO however to be trustworthy it’s sortof a black field. I’ve principally no clue how a lot I’m ingesting from a DAO standpoint. I used to be taking the Ancestral Health beef liver drugs and taking 6 capsules earlier than the meal. That appears to assist.

My second query is the extra essential one. How the heck do I cope with a histamine publicity. If I get received, I’ve anyplace from 24-48 hours of mind fog, excessive fatigue, malaise, and depressed/melancholy emotions. If there have been one thing that I may do put up publicity to abate this whereas I recuperate I’d be extraordinarily grateful. I discovered that if I take antihistamines (my rheumatologist really useful citrizine) that it helps *some* however not likely sufficient.

Thank you!

Jacob

Dry Fasting

Andrea writes:

Hey Robb and Nicki, I hoped you would possibly discuss dry fasting. I lately listened to a Dark Horse podcast the place Brett and Heather talked about their expertise dry fasting and have grow to be fairly taken with it. Since I significantly worth your capability to have a look at this stuff fairly and scientifically, I hoped you may share your ideas on the topic.

Thanks

Andrea

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